Taraxeryl acetate ( —— )

产品货号. M30896 CAS No. 2189-80-2

COA

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HNMR

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产品名称

Taraxeryl acetate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol.
产品描述

Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activity, could be attributed due to PTP1B inhibition by its triterpene constituents, betulin, betulinic acid and Taraxeryl acetate.
体外实验

Taraxerol acetate(10-150?μM; 24 or 48 hours)induces a dose- and time-dependent cytotoxic effects in the U87 cells, exhibits IC50 values of 34.2 and 28.4?μM, at 24 and 48 h, respectively.Taraxerol acetate(10, 50 and 150?μM; 24 hours)induces cell apoptosis, the percentage of apoptotic cells increased from 7.3% in the control cells, to 16.1, 44.1 and in the 10, 50 and 150?μM taraxerol acetate-treated cells, respectively. Furthermore, taraxerol acetate treatment led to sub-G1?cell cycle arrest with a corresponding decrease in the number of S-phase cells.
体内实验

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